Toxoplasmosis, a parasitic disease spread by cats, has become a significant concern for the endangered nene population in Hawaii. The nene, also known as the Hawaiian goose, is a protected species that is native to the islands. The disease is caused by the Toxoplasma gondii parasite, which is commonly found in cat feces. When cats infect the parasite, they can shed it in their feces, contaminating the environment and putting other animals at risk. The nene population is particularly vulnerable to toxoplasmosis due to their limited range and habitat. In addition to the nene, toxoplasmosis also poses a threat to public health, particularly for pregnant women and individuals with weakened immune systems. If infected, toxoplasmosis can cause serious health problems, including birth defects and miscarriage. The disease can also affect the brain and nervous system, leading to symptoms such as seizures and vision loss. Cats can become infected with toxoplasmosis through contact with contaminated feces, soil, or water. Once infected, they can shed the parasite in their feces for several weeks, putting other animals and humans at risk. The Hawaiian government has implemented measures to control the feral cat population, including spay and neuter programs and education campaigns. However, more needs to be done to address the growing threat of toxoplasmosis. Researchers are working to develop new methods for detecting and preventing the spread of the disease. This includes the use of genetic testing to identify infected cats and the development of vaccines to protect against toxoplasmosis. In the meantime, the public is being urged to take precautions to prevent the spread of the disease, including washing hands thoroughly after handling cat feces or contaminated soil. Pet owners are also being advised to keep their cats indoors and to dispose of feces properly. The impact of toxoplasmosis on the nene population and public health is a serious concern that requires immediate attention and action. By working together, researchers, policymakers, and the public can help to mitigate the threat of toxoplasmosis and protect the health and well-being of both humans and animals.